If
you’re carrying many extra pounds, you face a higher-than-average risk
of a whopping 50 different health problems. These health conditions
include the nation’s leading causes of death—heart disease, stroke,
diabetes, and certain cancers—as well as less common ailments such as
gout and gallstones. Perhaps even more compelling is the strong link
between excess weight and depression, because this common mood disorder
can have a profound, negative impact on your daily life.
A Harvard study that combined data from
more than 50,000 men (participants in the Health Professionals Follow-up
Study) and more than 120,000 women (from the Nurses’ Health Study)
revealed some sobering statistics about weight and health.
The volunteers provided their height and
weight, as well as details on their diets, health habits, and medical
histories. Researchers tracked the volunteers over more than 10 years.
They noted the occurrence of illnesses and compared those developments
with each subject’s body mass index (BMI)—an estimate of an individual’s
relative body fat calculated from his or her height and weight).
Obesity increased the risk of diabetes 20
times and substantially boosted the risk of developing high blood
pressure, heart disease, stroke, and gallstones. Among people who were
overweight or obese, there was a direct relationship between BMI and
risk: the higher the BMI, the higher the likelihood of disease.
Excess Weight Causes Many Health Problems
Weight and depression
Do people gain weight because they’re
depressed, or do they become depressed because they’re overweight? A
review of 15 studies found evidence that both scenarios are likely true.
The study, published in 2010 in the
Archives of General Psychiatry,
found that obese people have a 55% higher risk of developing depression
over time compared with people of normal weight. Here are some reasons
why obesity may increase risk of depression:
- Both conditions appear to stem (at least in part) from alterations in brain chemistry and function in response to stress.
- Psychological factors are also
plausible. In our culture, thin equals beautiful, and being overweight
can lower self-esteem, a known trigger for depression.
- Odd eating patterns and eating disorders, as well as the physical discomfort of being obese, are known to foster depression.
The study also found that depressed
people have a 58% higher risk of becoming obese. Here are some reasons
why depression may lead to obesity:
- Elevated levels of the stress
hormone cortisol (common in people with depression) may alter substances
in fat cells that make fat accumulation, especially in the belly, more
likely, according to one theory.
- People who feel depressed often feel too blue to eat properly and exercise regularly, making them more prone to gain weight.
- Some medications used to treat depression cause weight gain.
Sleep apnea: Why snoring can be serious
If you snore loudly and temporarily
stop breathing many times during the night, waking suddenly with a snort
or choke, you probably have sleep apnea, a common disorder that’s more
prevalent with overweight and obesity.
Your bedmate will probably notice
these symptoms, while you may not. People with sleep apnea don’t realize
they’ve been awakened because they don’t become fully conscious, but
these awakenings can disrupt sleep. Not only does
sleep apnea often lead to daytime sleepiness, it also increases the risk of high blood pressure, heart attack, and stroke.
Weight, heart disease, and stroke
Some of the most common problems seen in
people who carry excess weight, such as high blood pressure and
unhealthy levels of cholesterol and other fats in the blood, tend to
occur together. Both can lead to concurrent health problems—namely,
heart disease and stroke.
High blood pressure is about six times
more common in people who are obese than in those who are lean.
According to the American Heart Association, 22 pounds of excess weight
boosts systolic blood pressure (the first number in a reading) by an
average of 3 millimeters of mercury (mm Hg) and diastolic blood pressure
(the second number) by an average of 2.3 mm Hg, which translates to a
24% increase in stroke risk.
A 2007 study in
Archives of Internal Medicine
examined the connection between weight and heart disease by pooling
results from 21 different studies involving more than 300,000 people.
The study found:
- Being overweight boosted the risk of heart disease by 32%
- Obesity increased the risk by 81%
Although the adverse effects of
overweight on blood pressure and cholesterol levels could account for
45% of the increased heart disease risk, even modest amounts of excess
weight can increase the odds of heart disease independent of those
well-known risks, the authors concluded.
Compared with people of normal weight,
overweight people face a 22% higher risk of stroke. For those who are
obese, the increased risk rises to 64%, according to a 2010 report in
the journal
Stroke, which pooled results from 25 studies involving more than two million people.
Weight and diabetes
Overweight and obesity are so closely
linked to diabetes, experts have coined the term “diabesity” to describe
the phenomenon. About 90% of people with type 2 diabetes (the most
common form of the disease) are overweight or obese. The incidence of
diabetes rose dramatically—by nearly 65%—from 1996 to 2006.
A high blood sugar level, the hallmark of
diabetes, is one of the features of metabolic syndrome. If untreated or
poorly controlled, diabetes can lead to a number of grave health
problems, including kidney failure, blindness, and foot or leg
amputations. Diabetes is currently the seventh leading cause of death in
the United States.
Do you have metabolic syndrome?
Metabolic syndrome, a cluster of
conditions that occur together, also increases the risk of heart
disease, stroke, and diabetes. One of the key features is abdominal
obesity. If you have that problem, you’re more likely to have the other
characteristics.
You have metabolic syndrome if you have three or more of these five traits:
-
Big waist. A waist circumference more than 35 inches in women or 40 inches in men.
-
High triglycerides. A fasting blood triglyceride level of 150 milligrams/deciliter (mg/dL) or higher.
-
Low HDL. An HDL (“good”) cholesterol of less than 40 mg/dL in men or less than 50 mg/dL in women.
-
High blood pressure.
A systolic blood pressure (the top number of a reading) of 130 mm Hg or
higher, or diastolic (the lower number) of 85 mm Hg or higher.
-
High blood sugar. A fasting blood sugar level of 100 mg/dL or higher.
(Note: You are considered to have one
of the above traits if you receive treatment for it, even if your
numbers are normal with this treatment.)
Source: National Heart, Lung, and Blood Institute.
Weight and cancer
Some experts believe that obesity ranks as the second leading cause of cancer death, after cigarette smoking.
A study by the American Cancer Society, published in
The New England Journal of Medicine,
followed more than 900,000 people for 16 years. The study showed a link
between excess body weight and many different cancers. Some of the
findings:
- Among people ages 50 and older,
overweight and obesity may account for 14% of all cancer deaths in men
and 20% of all cancer deaths in women.
- In both men and women, higher BMIs
were associated with a higher risk of dying from cancer of the
esophagus, colon and rectum, liver, gallbladder, pancreas, or kidney.
- In men, excess weight also increased the risk of dying from stomach or prostate cancer.
- In women, deaths from cancer of the breast, uterus, cervix, or ovary were elevated in women with higher BMIs.
A 2008 review article in
The Lancet reached similar
conclusions. Part of the problem may lie in the fact that people who are
very overweight are less likely to have cancer screening tests such as
Pap smears and mammograms.
A report in
The International Journal of Obesity
showed that the larger the woman, the more likely she was to delay
getting a pelvic exam, largely because of negative experiences with
doctors and their office staff. In men, screening tests such as prostate
exams may be physically difficult if people are very overweight,
particularly if they tend to store fat in their hips, buttocks, or
thighs.
Weight and lifespan
Being overweight or obese can make just
getting around a challenge. Compared with people at a healthy weight,
those carrying extra pounds have a harder time walking a quarter-mile,
lifting 10 pounds, and rising from an armless chair. The burden of these
problems appears to be greater than in years past, probably because
people are now obese for a greater portion of their lives, experts
speculate.
And because excess weight plays a role in
so many common and deadly diseases, overweight and obesity can cut
years off your life. A
New England Journal of Medicine
study that followed more than half a million 50- to 71-year-olds for a
decade found an increase of 20% to 40% in death rates among people who
were overweight at midlife. Among obese people, the death rate was two
to three times as high.
A 2010 study in the same journal, which
pooled findings from 19 studies that followed nearly 1.5 million white
adults 19 to 84 years old for a similar period of time, found that the
risk of death increased along with body size, ranging from 44% higher
for those who were mildly obese to 250% higher for those with a BMI of
40 to 50.
Lose weight, feel better
Losing excess weight can make you
feel better both physically and emotionally and can help you live a
longer, healthier life. Especially encouraging is the fact that you
don’t have to lose a tremendous amount of weight to become healthier.
Even a modest weight loss of 5% to 10% of your starting weight can lead
to significant health benefits. Some examples:
- People with high blood pressure
who lost a modest 10 pounds over six months reduced their systolic blood
pressure by 2.8 mm Hg and their diastolic blood pressure by 2.5 mm Hg.
These reductions in blood pressure were equivalent to the reductions
brought about by treatment with some blood pressure medications.
- Weight loss is so effective that
many people with high blood pressure can stop taking blood pressure
medicine after they lose weight, for as long as they are able to keep it
off.
- In a study of people who were at
risk for type 2 diabetes, those who lost just 7% of their weight and
exercised about 30 minutes a day cut their risk of diabetes by nearly
60%.
KEY POINTS
- Excess pounds do more than increase your weight—they increase your risk of major health problems.
- People who are overweight or obese are more likely to have heart disease, strokes, diabetes, cancer, and depression.
- Fortunately, losing weight can reduce your risk of developing some of these problems.
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